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rho [2017-07-26 13:32:30]
transcriptional termination protein, involved in balanced regulation of cell motility, [SW|biofilm formation], and [SW|sporulation]
function
transcriptional termination
product
transcriptional termination protein
Genomic Context
categories
[category|SW 3|Information processing] → [category|SW 3.2|RNA synthesis and degradation] → [category|SW 3.2.1|Transcription] → [category|SW 3.2.1.3|Transcription elongation/ termination][category|SW 4|Lifestyles] → [category|SW 4.1|Exponential and early post-exponential lifestyles] → [category|SW 4.1.1|Motility and chemotaxis] → [category|SW 4.1.1.1|Signal transduction in motility and chemotaxis] → [category|SW 4.1.1.1.5|Additional chemotaxis signal transduction and regulatory proteins]Gene
Coordinates
3,803,400 → 3,804,683
Phenotypes of a mutant
loss of motility due to poor expression of the [SW|SigD regulon], this can be partially reversed by inactivation of [gene|920F91E748EE079FF864011D9052B073567C41E4|slrR] [pubmed|28723971]no [SW|biofilm formation], this can be suppressed by deletion of [gene|5A6FBAE6553343092862CB79E150F934978C32A9|sinR] and by switching of expression of the [gene|52A47B49B1FB955EE7E3C316B57A2B4134F78480|epsO]-[gene|F6C4634BF871D9A01E27014FFED7527C54BF560D|epsA] antisense transcript [pubmed|28723971]increased efficiency of [SW|sporulation], due to enhanced [protein|2C54FE2ADC82FF414D732018C90649D477A925AD|Spo0A] phosphorylation [pubmed|28723971]The protein
Protein family
rho family (according to Swiss-Prot)Structure
[PDB|1PVO] (Rho from ''E. coli'') [Pubmed|12859904]Expression and Regulation
Operons
genes
[gene|7CD46C64BE69EDADF58B634DC50C3F61BFFEC5B5|rho]-[gene|035154A4160F084BA1CC124D0951937B203E167D|rpmE]
description
[pubmed|22383849]
References
Reviews
16946247,12887917,16946247,8576105,23347833,12887917,23704790,26796109 Original publications
11566991,10027981,20075920,22383849,12859904,21040729,25112476,28723971 
